Journal article
Prognostic ability of 18F-FDG PET/CT in the assessment of colorectal liver metastases
V Muralidharan, M Kwok, ST Lee, L Lau, AM Scott, C Christophi
Journal of Nuclear Medicine | Published : 2012
Abstract
Modern multidisciplinary therapy for colorectal liver metastases (CRLM) is associated with significant morbidity and must be adapted to the patient's relative risk. The tools currently available to risk-stratify patients are limited. This study assessed the prognostic utility of metabolic measurements derived from 18FFDG PET compared with previously proposed prognostic scoring systems. Methods: Preoperative 18F-FDG PET/CT studies from a series of 30 patients who underwent liver resection for CRLM after neoadjuvant chemotherapy were evaluated. Quantitative 18F-FDG PET analysis calculated the maximum and mean standardized uptake value, metabolic tumor volume (MTV), and tumor glycolytic volume ..
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Awarded by NHMRC
Funding Acknowledgements
We thank the members of the Hepato-Pancreato-Biliary and Transplant Unit, Austin Hospital, including Roger Berry, Michael Fink, Mehrdad Nikfarjam, Robert Jones, and Mark Goodwin from the Department of Radiology and Niall Tebbutt from GI Oncology, for their clinical contribution to this study, as well as the staff of the Centre for PET, Austin Hospital. This study was supported in part by NHMRC Program Grant 487922 and OIS funding from the Victorian Government. No other potential conflict of interest relevant to this article was reported.